Heart Murmurs: Innocent or Pathologic

BACKGROUND: Many normal children have heart murmurs.Most of these murmurs are innocent but differentiation of innocent murmurs from those due to structural heart disease, pathological murmurs, is important.Some clinicians do not refer the suspected patients to cardiologist due to anxiety-provoking for the family.The aim of this study was to Rainshe

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Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome

DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans.On top of that, the DNA methylome undergoes profound changes in cancer and other Card Readers disorders.However, large-scale and population-based studies are limited by h

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